stackin stock

Sentinel

Immune modulation. Thymosin Alpha-1 + LL-37.

$185Thymosin Alpha-1 · LL-37

// tl;dr

Two peptides for immune balance. Thymosin Alpha-1 tunes the targeted (adaptive) immune response; LL-37 reinforces the first-line (innate) defense.

// what's in the stack

// about

Adaptive (Thymosin Alpha-1, T-cell modulation) plus innate (LL-37, cathelicidin antimicrobial) in one stack. Two orthogonal mechanisms targeting both arms of the immune system.

// structures

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28 residues
// NMR · PDB 2L9I · 21 models
N-SDAAVDTSSEITTKDLKEKKEVVEEAEN-C
  • hydrophobic
  • polar
  • positive
  • negative
  • special

28 residues. N-terminus is acetylated in the native peptide. The morph cycles through plausible low-frequency conformations - illustrative flexibility, not the experimentally resolved ensemble. Bead brightness scales with per-residue RMSF: the dimmer the residue, the more rigid it is in the ensemble.

// synergy

T-cell maturation · adaptive immunitycathelicidin · innate immunityThymosin A…LL-37balanced immunedefense

One arm of the immune system per peptide. Adaptive (Tα-1) plus innate (LL-37) - both layers of immune defense covered without dialing either past physiologic levels.

// research deep-dive

Read the mechanism in detail

// questions

// for research purposes only. not for human consumption.
// not intended to diagnose, treat, cure, or prevent any disease.